Technology
The Chempaq XBC (eXpress Blood Counter) comprises a small disposable cassette: the PAQ (Particle Analyzer and Quantifier), and a Reader at the size of a desk telephone.
The Reader is based on a unique, patented sensor technology which enables precise, quick and easy-to-perform hematology testing.
The basic principle involved in the Chempaq XBC technology was invented by Wallace Coulter in 1958 and is normally called the Coulter principle or impedance cell counting and sizing.
The impedance principle is used in the majority of the hematology analyzers available today, but all these comprise complex liquid handling and control. The Chempaq PAQ-system provides a unique way of avoiding complex liquid handling, and enables miniaturizing the device for point-of-care tests.
The principle is based on the change in impedance as cells suspended in a conductive liquid are aspirated through a narrow path, called the aperture, formed in an electrically isolated membrane. A cell passing through the aperture will change the impedance and cause an electric pulse with amplitude proportional to the cell volume.
Chempaq XBC additionally uses photometry measurement, which is used for the assessment of the hemoglobin content.
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